Pilot study on identification of Aspergillus species and its antifungal drug sensitivity testing by disc diffusion method

Aspergillus species are frequent causes of invasive fungal infections in immunocompromised patients; they are also associated with allergic bronchopulmonary diseases, mycotic keratitis, otomycosis and nasal sinusitis. At least 30 Aspergillus species have been associated with human diseases, and A. fumigatus remains the most frequent cause of invasive Aspergillosis (IA) but recently in some institutions, A. tereus is becoming more common and it is less susceptible to Amphotericine B. A. nidulans has also been reported to be less susceptible to this drug in comparison with A. fumigatus. A. ustus as a rare cause of invasive disease has been, reported to be resistant to Amphotericine-B while remaining susceptible to itraconazole. A. ustus has also been reported to be less susceptible to voriconazole. Therefore accurate identification of species is International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 3 Number 12 (2014) pp. 555-562 http://www.ijcmas.com